PUB1/YNL016W Summary Help

PUB1 BASIC INFORMATION

Standard Name PUB1 1
Systematic Name YNL016W
Alias RNP1
Feature Type ORF, Verified
Description Poly (A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly (1, 2, 3, 4)
Name Description PolyUridylate Binding 1
GO Annotations All PUB1 GO evidence and references
    View Computational GO annotations for PUB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PUB1 Phenotype details and references
Large-scale survey
null
Interactions PUB1 All interactions details and references
71 total interaction(s) for 63 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • PCA: 15
  • Reconstituted Complex: 1
  • Two-hybrid: 5
Genetic Interactions
  • Phenotypic Enhancement: 13
  • Phenotypic Suppression: 7
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 1
Sequence Information
ChrXIV:602909 to 604270 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2010-01-05 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1362 602909..604270 2010-01-05 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004961

PUB1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for PUB1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
RNP1Nomenclature conflictRNP1 has been used in the literature to refer to both PUB1/YNL016W, which encodes a poly(U) binding protein and RNP1/YLL046C, which encodes a ribonucleoprotein.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PUB1]

1) Matunis MJ, et al.  (1993) PUB1: a major yeast poly(A)+ RNA-binding protein. Mol Cell Biol 13(10):6114-23
2) Anderson JT, et al.  (1993) PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae. Mol Cell Biol 13(10):6102-13
3) Duttagupta R, et al.  (2005) Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Mol Cell Biol 25(13):5499-513
4) Buchan JR, et al.  (2008) P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol 183(3):441-55