YNG2/YHR090C Summary Help

YNG2 BASIC INFORMATION

Standard Name YNG2
Systematic Name YHR090C
Alias NBN1 , EAF4 1
Feature Type ORF, Verified
Description Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5 (2, 3, 4)
Name Description Yeast homolog of mammalian Ing1
GO Annotations All YNG2 GO evidence and references
    View Computational GO annotations for YNG2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Interactions YNG2 All interactions details and references
348 total interaction(s) for 252 unique genes/features.
Physical Interactions
  • Affinity Capture-Luminescence: 4
  • Affinity Capture-MS: 36
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 23
  • Biochemical Activity: 10
  • Co-purification: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 2
Genetic Interactions
  • Phenotypic Enhancement: 30
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 89
  • Synthetic Lethality: 133
  • Synthetic Rescue: 14
Sequence Information
ChrVIII:284627 to 283779 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..849 284627..283779 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001132

YNG2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for YNG2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YNG2]

1) Nourani A, et al.  (2001) Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol Cell Biol 21(22):7629-40
2) Loewith R, et al.  (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16
3) Nourani A, et al.  (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5
4) Gordon PM, et al.  (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426