Standard Name	YND1 1
Systematic Name	YER005W
Alias	APY1 2 , YEJ5
Feature Type	ORF, Verified
Description	Apyrase with wide substrate specificity, helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity (1, 3)
Name Description	Yeast Nucleoside Diphosphatase 1

Chromosomal Location	ChrV:160550 to 162442 | ORF Map | GBrowse

	View Computational GO annotations for YND1
Molecular Function
Manually curated	nucleoside-diphosphatase activity (IDA) nucleoside-triphosphatase activity (IDA)
Biological Process
Manually curated	protein glycosylation (IMP)
Cellular Component
Manually curated	Golgi membrane (IDA) membrane (IDA)
High-throughput	colocalizes_with COPI-coated vesicle (IDA) Golgi apparatus (IDA)

Classical genetics
null	resistance to trisodium vanadate: increased resistance to hygromycin B: decreased vegetative growth: decreased
Large-scale survey
null	competitive fitness: increased competitive fitness: decreased dessication resistance: decreased filamentous growth: decreased invasive growth: absent Fus-Mid-GFP distribution: abnormal resistance to acetic acid: increased resistance to quinine: decreased resistance to dimethyl sulfoxide: decreased stress resistance: decreased vacuolar morphology: abnormal viable
overexpression	inviable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	81 total interaction(s) for 61 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 1 PCA: 9 Two-hybrid: 1
Genetic Interactions	Dosage Growth Defect: 2 Dosage Lethality: 1 Dosage Rescue: 1 Negative Genetic: 54 Phenotypic Enhancement: 1 Positive Genetic: 3 Synthetic Growth Defect: 3 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:160550 to 162442 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1893 160550..162442 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000807