JNM1/YMR294W Summary Help

Standard Name JNM1 1
Systematic Name YMR294W
Alias INS1 , PAC3 2
Feature Type ORF, Verified
Description Component of the yeast dynactin complex; consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B (1, 3)
Name Description Just Nuclear Migration 1
Chromosomal Location
ChrXIII:856966 to 858087 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All JNM1 GO evidence and references
  View Computational GO annotations for JNM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
495 total interaction(s) for 290 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 11
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Two-hybrid: 39

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 209
  • Phenotypic Suppression: 1
  • Positive Genetic: 27
  • Synthetic Growth Defect: 41
  • Synthetic Lethality: 159

Resources
Expression Summary
histogram
Resources
Length (a.a.) 373
Molecular Weight (Da) 43,607
Isoelectric Point (pI) 4.66
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:856966 to 858087 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1122 856966..858087 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004908
References cited on this page View Complete Literature Guide for JNM1
1) McMillan JN and Tatchell K  (1994) The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle. J Cell Biol 125(1):143-58
2) Geiser JR, et al.  (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8(6):1035-50
3) Kahana JA, et al.  (1998) The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell 9(7):1741-56