RIT1/YMR283C Summary

RIT1 BASIC INFORMATION

Standard Name	RIT1 1, 2
Systematic Name	YMR283C
Feature Type	ORF, Verified
Description	2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA (1, 3)
Name Description	Ribosylation of Initiator tRNA 1
Gene Product Alias	initiator methionine tRNA 2'-O-ribosyl phosphate transferase 1

GO Annotations	All RIT1 GO evidence and references
	View Computational GO annotations for RIT1
Molecular Function
Manually curated	transferase activity, transferring pentosyl groups (IDA, IGI, IMP)
Biological Process
Manually curated	charged-tRNA amino acid modification (IGI, IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Mutant Phenotype	All RIT1 Phenotype details and references
Large-scale survey
null	viable

Interactions	RIT1 All interactions details and references
	36 total interaction(s) for 32 unique genes/features.
Genetic Interactions	Dosage Lethality: 1 Phenotypic Enhancement: 24 Phenotypic Suppression: 6 Synthetic Growth Defect: 5

Sequence Information

ChrXIII:836866 to 835325 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1542	836866..835325	2004-02-27	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004896

RIT1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RIT1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RIT1]

1)	Astrom SU and Bystrom AS (1994) Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination. Cell 79(3):535-46
2)	Astrom, S. (1993) Personal Communication, Mortimer Map Edition 12
3)	Astrom SU, et al. (1999) Genetic interactions between a null allele of the RIT1 gene encoding an initiator tRNA-specific modification enzyme and genes encoding translation factors in Saccharomyces cerevisiae. Mol Gen Genet 261(6):967-76

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