GPI12/YMR281W Summary

GPI12 BASIC INFORMATION

Standard Name	GPI12
Systematic Name	YMR281W
Feature Type	ORF, Verified
Description	ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp (1)
Name Description	GlycosylPhosphatidylInositol anchor biosynthesis 1

GO Annotations	All GPI12 GO evidence and references
	View Computational GO annotations for GPI12
Molecular Function
Manually curated	N-acetylglucosaminylphosphatidylinositol deacetylase activity (ISS)
Biological Process
Manually curated	GPI anchor biosynthetic process (ISS)
Cellular Component
Manually curated	endoplasmic reticulum membrane (ISS)

Mutant Phenotype	All GPI12 Phenotype details and references
Large-scale survey
conditional	heat sensitivity: increased
null	inviable
overexpression	filamentous growth: increased

Interactions	GPI12 All interactions details and references
	1 total interaction(s) for 1 unique genes/features.
Physical Interactions	Biochemical Activity: 1

Sequence Information

ChrXIII:832338 to 833252 | |

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..915	832338..833252	2004-02-27	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004894

GPI12 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for GPI12

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GPI12]

1)	Watanabe R, et al. (1999) Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis. Biochem J 339 ( Pt 1)():185-92

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