FCP1/YMR277W Summary

FCP1 BASIC INFORMATION

Standard Name	FCP1
Systematic Name	YMR277W
Feature Type	ORF, Verified
Description	Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p) (1)

GO Annotations	All FCP1 GO evidence and references
	View Computational GO annotations for FCP1
Molecular Function
Manually curated	phosphatase activity (TAS) phosphoprotein phosphatase activity (IDA)
Biological Process
Manually curated	protein amino acid dephosphorylation (IDA) transcription (IMP)
Cellular Component
Manually curated	nucleus (IPI)

Mutant Phenotype	All FCP1 Phenotype details and references
Classical genetics
overexpression	budding: abnormal cell cycle progression in G1 phase: abnormal
Large-scale survey
null	inviable
overexpression	inviable

Interactions	FCP1 All interactions details and references
	44 total interaction(s) for 37 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Biochemical Activity: 1 Protein-peptide: 1 Reconstituted Complex: 4 Two-hybrid: 3
Genetic Interactions	Dosage Rescue: 5 Phenotypic Enhancement: 2 Phenotypic Suppression: 5 Synthetic Growth Defect: 12 Synthetic Lethality: 8

Sequence Information

ChrXIII:820255 to 822453 | |

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2199	820255..822453	2004-02-27	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004890

FCP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for FCP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for FCP1]

1)	Kops O, et al. (2002) Pin1 modulates the dephosphorylation of the RNA polymerase II C-terminal domain by yeast Fcp1. FEBS Lett 513(2-3):305-11

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