TMA23/YMR269W Summary Help

Standard Name TMA23 1
Systematic Name YMR269W
Alias YMR268W-A
Feature Type ORF, Verified
Description Nucleolar protein implicated in ribosome biogenesis; deletion extends chronological lifespan (1, 2, 3)
Name Description Translation Machinery Associated 2
Chromosomal Location
ChrXIII:804456 to 805091 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TMA23 GO evidence and references
  View Computational GO annotations for TMA23
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 52 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
133 total interaction(s) for 101 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • PCA: 5
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 88
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 3
  • Positive Genetic: 22
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 211
Molecular Weight (Da) 23,949
Isoelectric Point (pI) 10.94
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:804456 to 805091 | ORF Map | GBrowse
This feature contains embedded feature(s): YMR268W-A
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2004-02-27
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..636 804456..805091 2011-02-03 2004-02-27
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004882
References cited on this page View Complete Literature Guide for TMA23
1) Buchhaupt M, et al.  (2007) Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. FEMS Yeast Res 7(6):771-81
2) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307
3) Burtner CR, et al.  (2011) A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9):1385-96