RNH1/YMR234W Summary Help

Standard Name RNH1
Systematic Name YMR234W
Feature Type ORF, Verified
Description Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I. (1, 2, 3)
Name Description RNase H
Chromosomal Location
ChrXIII:740266 to 741312 | ORF Map | GBrowse
Gbrowse
Genetic position: 160 cM
Gene Ontology Annotations All RNH1 GO evidence and references
  View Computational GO annotations for RNH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
unspecified
Resources
57 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 6
  • Phenotypic Enhancement: 4
  • Phenotypic Suppression: 22
  • Positive Genetic: 1
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 10
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 348
Molecular Weight (Da) 39,431
Isoelectric Point (pI) 10.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:740266 to 741312 | ORF Map | GBrowse
SGD ORF map
Genetic position: 160 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1047 740266..741312 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004847
References cited on this page View Complete Literature Guide for RNH1
1) Cerritelli SM and Crouch RJ  (1995) The non-RNase H domain of Saccharomyces cerevisiae RNase H1 binds double-stranded RNA: magnesium modulates the switch between double-stranded RNA binding and RNase H activity. RNA 1(3):246-59
2) Itaya M, et al.  (1991) Selective cloning of genes encoding RNase H from Salmonella typhimurium, Saccharomyces cerevisiae and Escherichia coli rnh mutant. Mol Gen Genet 227(3):438-45
3) Huet J, et al.  (1977) Characterization of ribonuclease H activity associated yeast RNA polymerase A. J Biol Chem 252(24):8848-55