Standard Name	REC114
Systematic Name	YMR133W
Feature Type	ORF, Verified
Description	Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division (1, 2, 3)
Name Description	RECombination 3

Chromosomal Location	ChrXIII:536207 to 537609 | ORF Map | GBrowse
	Genetic position: 91 cM

	View Computational GO annotations for REC114
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	meiotic DNA double-strand break formation (TAS) reciprocal meiotic recombination (IMP)
Cellular Component
Manually curated	condensed nuclear chromosome (IDA)

Classical genetics
reduction of function	spore germination: decreased sporulation: decreased
Large-scale survey
null	competitive fitness: decreased vegetative growth: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 14 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2 Two-hybrid: 8
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 4 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Positive Genetic: 2 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:536207 to 537609 | ORF Map | GBrowse
	Genetic position: 91 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1999-07-17
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1242 536207..537448 2011-02-03 1999-07-17 Intron 1243..1358 537449..537564 2011-02-03 1999-07-17 CDS 1359..1403 537565..537609 2011-02-03 1999-07-17
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (1243 - 1358)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004740