Standard Name	BUD22 1
Systematic Name	YMR014W
Feature Type	ORF, Verified
Description	Protein required for 18S rRNA maturation and small ribosomal subunit biogenesis; cosediments with pre-ribosomal particles; mutation decreases efficiency of +1 Ty1 frameshifting and transposition, and affects budding pattern (1, 2, 3)
Name Description	BUD site selection 1

Chromosomal Location	ChrXIII:298868 to 300427 | ORF Map | GBrowse

	View Computational GO annotations for BUD22
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	maturation of SSU-rRNA (IMP) ribosomal small subunit biogenesis (IMP)
Cellular Component
Manually curated	90S preribosome (IDA) nucleus (IDA)
High-throughput	nucleolus (IDA)

Classical genetics
null	35S pre-rRNA accumulation: increased nuclear export: decreased Gag protein accumulation: decreased 40S ribosomal subunit accumulation: decreased resistance to paromomycin: decreased resistance to neomycin: decreased transposable element transposition: decreased vegetative growth: decreased rate
Large-scale survey
null	auxotrophy budding pattern: abnormal cell cycle progression in G1 phase: increased duration cell size: decreased cell size: increased dessication resistance: decreased resistance to amitrole: decreased resistance to 4-chlorophenol: decreased resistance to L-1,4-dithiothreitol: decreased resistance to cycloheximide: decreased resistance to oleate: decreased resistance to doxorubicin: decreased resistance to benomyl: decreased resistance to acrolein: decreased stress resistance: increased transposable element transposition: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
overexpression	filamentous growth: increased invasive growth: absent
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	13 total interaction(s) for 12 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-RNA: 2
Genetic Interactions	Dosage Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:298868 to 300427 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1560 298868..300427 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004616