MDM1/YML104C Summary Help

Standard Name MDM1 1
Systematic Name YML104C
Feature Type ORF, Verified
Description Intermediate filament protein; required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P) (2, 3, 4)
Name Description Mitochondrial Distribution and Morphology 1
Chromosomal Location
ChrXIII:62322 to 58939 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All MDM1 GO evidence and references
  View Computational GO annotations for MDM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
40 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Two-hybrid: 28

Genetic Interactions
  • Negative Genetic: 4
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,127
Molecular Weight (Da) 129,979
Isoelectric Point (pI) 6.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:62322 to 58939 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3384 62322..58939 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004572
References cited on this page View Complete Literature Guide for MDM1
1) McConnell SJ, et al.  (1990) Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J Cell Biol 111(3):967-76
2) McConnell SJ and Yaffe MP  (1993) Intermediate filament formation by a yeast protein essential for organelle inheritance. Science 260(5108):687-9
3) Fisk HA and Yaffe MP  (1997) Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance. J Cell Biol 138(3):485-94
4) Yu JW and Lemmon MA  (2001) All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate. J Biol Chem 276(47):44179-84