PSP2/YML017W Summary Help

Standard Name PSP2 1
Systematic Name YML017W
Alias MRS15
Feature Type ORF, Verified
Description Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing (1, 2)
Name Description Polymerase SuPpressor 1
Chromosomal Location
ChrXIII:236588 to 238731 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PSP2 GO evidence and references
  View Computational GO annotations for PSP2
Molecular Function
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
repressible
Resources
72 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 2
  • PCA: 2

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 35
  • Positive Genetic: 5
  • Synthetic Growth Defect: 9
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 593
Molecular Weight (Da) 65,584
Isoelectric Point (pI) 9.54
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:236588 to 238731 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2004-01-30 | Sequence: 2004-01-30
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4 236588..236591 2004-01-30 2004-01-30
Intron 5..366 236592..236953 2004-01-30 2004-01-30
CDS 367..2144 236954..238731 2004-01-30 2004-01-30
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004479
References cited on this page View Complete Literature Guide for PSP2
1) Formosa T and Nittis T  (1998) Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. Mol Gen Genet 257(4):461-8
2) Waldherr M, et al.  (1993) A multitude of suppressors of group II intron-splicing defects in yeast. Curr Genet 24(4):301-6