YMC1/YPR058W Summary Help

Standard Name YMC1 1
Systematic Name YPR058W
Feature Type ORF, Verified
Description Putative mitochondrial inner membrane transporter; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; localizes to vacuole in response to H2O2; YMC1 has a paralog, YMC2, that arose from the whole genome duplication (1, 2, 3, 4, 5, 6)
Name Description Yeast Mitochondrial Carrier 1
Chromosomal Location
ChrXVI:673751 to 674674 | ORF Map | GBrowse
Gbrowse
Genetic position: 39.7 cM
Gene Ontology Annotations All YMC1 GO evidence and references
  View Computational GO annotations for YMC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
overexpression
Resources
25 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 6
  • PCA: 2

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 3
  • Negative Genetic: 6
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 307
Molecular Weight (Da) 33,375
Isoelectric Point (pI) 10.14
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:673751 to 674674 | ORF Map | GBrowse
SGD ORF map
Genetic position: 39.7 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..924 673751..674674 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006262
References cited on this page View Complete Literature Guide for YMC1
1) Graf R, et al.  (1993) YMC1, a yeast gene encoding a new putative mitochondrial carrier protein. Yeast 9(3):301-5
2) El Moualij B, et al.  (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81
3) Trotter PJ, et al.  (2005) Mitochondrial transporters involved in oleic acid utilization and glutamate metabolism in yeast. Arch Biochem Biophys 442(1):21-32
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
6) Breker M, et al.  (2013) A novel single-cell screening platform reveals proteome plasticity during yeast stress responses. J Cell Biol 200(6):839-50