NBP1/YLR457C Summary

NBP1 BASIC INFORMATION

Standard Name	NBP1 1
Systematic Name	YLR457C
Feature Type	ORF, Verified
Description	Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex (1, 2)
Name Description	Nap1 Binding Protein 1

GO Annotations	All NBP1 GO evidence and references
	View Computational GO annotations for NBP1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	spindle pole body duplication in nuclear envelope (IGI, IMP, IPI)
Cellular Component
Manually curated	central plaque of spindle pole body (IDA) nucleus (IDA) spindle pole body (IDA)

Mutant Phenotype	All NBP1 Phenotype details and references
Classical genetics
null	inviable
Large-scale survey
null	inviable
overexpression	filamentous growth: increased

Interactions	NBP1 All interactions details and references
	22 total interaction(s) for 16 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2 Biochemical Activity: 4 Co-localization: 1 Two-hybrid: 9
Genetic Interactions	Dosage Rescue: 6

Sequence Information

ChrXII:1056769 to 1055810 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2006-01-09 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..960	1056769..1055810	2006-01-09	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004449

NBP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NBP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NBP1]

1)	Shimizu Y, et al. (2000) NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization. Gene 246(1-2):395-404
2)	Araki Y, et al. (2006) The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. Mol Biol Cell 17(4):1959-70

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