YLR456W Summary Help

Systematic Name YLR456W
Feature Type ORF, Uncharacterized
Description Putative pyridoxal 5'-phosphate synthase; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2; YLR456W has a paralog, YPR172W, that arose from the whole genome duplication (1, 2)
Chromosomal Location
ChrXII:1055070 to 1055684 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YLR456W GO evidence and references
  View Computational GO annotations for YLR456W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Large-scale survey
null
Resources
13 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • Two-hybrid: 5

Genetic Interactions
  • Negative Genetic: 4
  • Phenotypic Enhancement: 1
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 204
Molecular Weight (Da) 23,293
Isoelectric Point (pI) 6.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:1055070 to 1055684 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..615 1055070..1055684 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004448
References cited on this page View Complete Literature Guide for YLR456W
1) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
2) Chamilos G, et al.  (2008) Genomewide Screening for Genes Associated with Gliotoxin Resistance and Sensitivity in Saccharomyces cerevisiae. Antimicrob Agents Chemother 52(4):1325-9