YLR422W Summary Help

Reserved Name DCK1 1

This name is reserved with SGD according to the Gene Naming Guidelines agreed upon by the yeast community.
For more information about this reservation, please see the Locus History.

Systematic Name YLR422W
Feature Type ORF, Uncharacterized
Description Protein of unknown function with similarity to human DOCK proteins; interacts with Ino4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, YLR422W is not an essential protein; DOCK proteins act as guanine nucleotide exchange factors (2, 3, 4)
Name Description DOCK1 homolog 1
Chromosomal Location
ChrXII:965897 to 971695 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YLR422W GO evidence and references
  View Computational GO annotations for YLR422W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
Resources
31 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 19
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,932
Molecular Weight (Da) 221,561
Isoelectric Point (pI) 7.72
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:965897 to 971695 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..5799 965897..971695 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004414
References cited on this page View Complete Literature Guide for YLR422W
1) Jendretzki A, et al.  (2012) The Saccharomyces cerevisiae homologue of the DOCK/ELMO complex is a putative GEF for the small GTPase Rho5 ()
2) Robinson KA, et al.  (2000) A network of yeast basic helix-loop-helix interactions. Nucleic Acids Res 28(22):4460-6
3) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
4) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91