| Standard Name | ART10 1 |
|---|---|
| Systematic Name | YLR392C |
| Feature Type | ORF, Verified |
| Description | Protein of unknown function that contains 2 PY motifs and is ubiquinated by Rsp5p; overexpression confers resistance to arsenite; green fluorescent protein (GFP)-fusion protein localizes it to the cytoplasm; non-essential gene (1, 2, 3, 4) |
| Name Description | Arrestin-Related Trafficking adaptors 5 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All ART10 GO evidence and references
| View Computational GO annotations for ART10 | |
| Molecular Function | |
| Manually curated |
|
| Biological Process | |
| Manually curated |
|
| Cellular Component | |
| High-throughput |
Mutant phenotypes All ART10 Phenotype evidence and references
| Classical genetics | |
|---|---|
| overexpression | |
| Large-scale survey | |
| null | |
| overexpression | |
| Resources |
interactions All ART10 Interaction evidence and references
| 15 total interaction(s) for 9 unique genes/features. | |
| Physical Interactions |
|
| Genetic Interactions |
|
| Resources |
|
Expression Summary
|
| |
| Resources |
Protein Information All ART10 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
|
| |||||||||||||
| Last Update | Coordinates: 2004-02-05 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
| ||||||||||||
| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
|---|
| Primary SGDID | S000004384 |
|---|
References cited on this page View Complete Literature Guide for ART10
| 1) | Nikko E and Pelham HR (2009) Arrestin-mediated endocytosis of yeast plasma membrane transporters. Traffic 10(12):1856-67 |
| 2) | Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 |
| 3) | Gupta R, et al. (2007) Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Mol Syst Biol 3:116 |
| 4) | Takahashi T, et al. (2010) Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae. J Toxicol Sci 35(6):945-6 |
| 5) | Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 |






