ART10/YLR392C Summary Help

Standard Name ART10 1
Systematic Name YLR392C
Feature Type ORF, Verified
Description Protein of unknown function that contains 2 PY motifs; ubiquinated by Rsp5p; overexpression confers resistance to arsenite; green fluorescent protein (GFP)-fusion protein localizes it to the cytoplasm; non-essential gene (1, 2, 3, 4)
Name Description Arrestin-Related Trafficking adaptors 5
Chromosomal Location
ChrXII:906305 to 904749 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ART10 GO evidence and references
  View Computational GO annotations for ART10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 1 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
overexpression
Resources
18 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Biochemical Activity: 1
  • Co-purification: 1
  • Protein-peptide: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 518
Molecular Weight (Da) 59,758
Isoelectric Point (pI) 9.46
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:906305 to 904749 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1557 906305..904749 2004-02-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004384
References cited on this page View Complete Literature Guide for ART10
1) Nikko E and Pelham HR  (2009) Arrestin-mediated endocytosis of yeast plasma membrane transporters. Traffic 10(12):1856-67
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Gupta R, et al.  (2007) Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Mol Syst Biol 3:116
4) Takahashi T, et al.  (2010) Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae. J Toxicol Sci 35(6):945-6
5) Lin CH, et al.  (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25