YLR278C Summary

YLR278C BASIC INFORMATION

Systematic Name	YLR278C
Feature Type	ORF, Uncharacterized
Description	Zinc-cluster protein; GFP-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; has a prion-domain like fragment that increases frequency of [URE3]; YLR278C is not an essential gene (1, 2, 3, 4)

GO Annotations	All YLR278C GO evidence and references
	View Computational GO annotations for YLR278C
Molecular Function
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
High-throughput	nucleus (IDA)

Mutant Phenotype	All YLR278C Phenotype details and references
Classical genetics
null	resistance to caffeine: decreased viable
Large-scale survey
null	resistance to 4-nitroquinoline N-oxide: normal resistance to oligomycin: normal resistance to rhodamine 6-G: normal resistance to chloramphenicol: normal resistance to ketoconazole: normal resistance to cycloheximide: normal toxin resistance: increased viable

Interactions	YLR278C All interactions details and references
	14 total interaction(s) for 14 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Biochemical Activity: 2
Genetic Interactions	Phenotypic Enhancement: 5 Phenotypic Suppression: 1

Sequence Information

ChrXII:704026 to 700001 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..4026	704026..700001	2004-02-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004268

YLR278C RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for YLR278C

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YLR278C]

1)	Akache B, et al. (2001) Phenotypic analysis of genes encoding yeast zinc cluster proteins. Nucleic Acids Res 29(10):2181-90
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3)	Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
4)	Ross CD, et al. (2009) A Promiscuous Prion: Efficient Induction of [URE3] Prion Formation by Heterologous Prion Domains. Genetics 183(3):929-40

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