DBP9/YLR276C Summary Help

Standard Name DBP9 1
Systematic Name YLR276C
Feature Type ORF, Verified
Description DEAD-box protein required for 27S rRNA processing; exhibits DNA, RNA and DNA/RNA helicase activities; ATPase activity shows preference for DNA over RNA; DNA helicase activity abolished by mutation in RNA-binding domain (1, 2)
Name Description Dead Box Protein 1
Chromosomal Location
ChrXII:696830 to 695046 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DBP9 GO evidence and references
  View Computational GO annotations for DBP9
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
null
repressible
Large-scale survey
conditional
null
reduction of function
unspecified
Resources
109 total interaction(s) for 89 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 60
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 2
  • Biochemical Activity: 7
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 32
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 594
Molecular Weight (Da) 68,059
Isoelectric Point (pI) 9.97
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:696830 to 695046 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1785 696830..695046 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004266
References cited on this page View Complete Literature Guide for DBP9
1) Daugeron MC, et al.  (2001) Dbp9p, a putative ATP-dependent RNA helicase involved in 60S-ribosomal-subunit biogenesis, functionally interacts with Dbp6p. RNA 7(9):1317-34
2) Kikuma T, et al.  (2004) Dbp9p, a member of the DEAD box protein family, exhibits DNA helicase activity. J Biol Chem 279(20):20692-8