TMA7/YLR262C-A Summary Help

Standard Name TMA7 1
Systematic Name YLR262C-A
Feature Type ORF, Verified
Description Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin; protein abundance increases in response to DNA replication stress (1, 2)
Name Description Translation Machinery Associated 1
Chromosomal Location
ChrXII:669662 to 669468 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TMA7 GO evidence and references
  View Computational GO annotations for TMA7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
22 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 3
  • PCA: 3

Genetic Interactions
  • Negative Genetic: 11
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 64
Molecular Weight (Da) 6,941
Isoelectric Point (pI) 11.05
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:669662 to 669468 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1999-07-17
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..195 669662..669468 2011-02-03 1999-07-17
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Retired NameRBF7
Primary SGDIDS000007246
References cited on this page View Complete Literature Guide for TMA7
1) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76