Standard Name	PBA1 1
Systematic Name	YLR199C
Alias	POC1 2
Feature Type	ORF, Verified
Description	Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly (1)
Name Description	Proteasome Biogenesis-Associated 1

Chromosomal Location	ChrXII:548769 to 547853 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for PBA1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	proteasome assembly (IGI, ISS)
Cellular Component
High-throughput	cytoplasm (IDA)

Classical genetics
null	resistance to 4-nitroquinoline N-oxide: increased resistance to methyl methanesulfonate: increased resistance to camptothecin: increased resistance to canavanine: normal resistance to (-)-anisomycin: increased resistance to chloramphenicol: increased viable
Large-scale survey
null	anaerobic growth: decreased auxotrophy competitive fitness: decreased haploinsufficient heat sensitivity: increased resistance to trichothecene: increased resistance to benzo[a]pyrene: increased resistance to 4-chlorophenol: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	42 total interaction(s) for 31 unique genes/features.
Physical Interactions	Affinity Capture-MS: 16 Affinity Capture-RNA: 2 Affinity Capture-Western: 3 Co-crystal Structure: 1 Co-fractionation: 2 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 11 Positive Genetic: 1 Synthetic Growth Defect: 4 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:548769 to 547853 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 2003-09-27
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..6 548769..548764 2011-02-03 2003-09-27 Intron 7..92 548763..548678 2011-02-03 2003-09-27 CDS 93..917 548677..547853 2011-02-03 2003-09-27
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (7 - 92)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004189