Standard Name	CCW12 1
Systematic Name	YLR110C
Feature Type	ORF, Verified
Description	Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	Covalently linked Cell Wall protein 1

Chromosomal Location	ChrXII:370098 to 369697 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CCW12
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	agglutination involved in conjugation with cellular fusion (IMP) conjugation with cellular fusion (IMP) fungal-type cell wall organization (IMP)
Cellular Component
Manually curated	cellular bud tip (IDA) fungal-type cell wall (IDA) mating projection tip (IDA)

Classical genetics
null	bud morphology: abnormal cell wall morphology: abnormal chitin deposition: increased chronological lifespan: increased hypoosmotic stress resistance: decreased mating efficiency: decreased mating projection morphology: abnormal resistance to Congo Red: decreased resistance to Calcofluor White: decreased resistance to enzymatic treatment: decreased vegetative growth: decreased rate vegetative growth: decreased viability: decreased
Large-scale survey
null	bud morphology: abnormal budding pattern: abnormal cell shape: abnormal chitin deposition: increased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate haploinsufficient heat sensitivity: increased protein transport: abnormal resistance to hygromycin B: decreased resistance to doxorubicin: decreased resistance to mycophenolic acid: decreased resistance to sodium arsenite: increased resistance to nickel sulfate: decreased resistance to PM02734: decreased resistance to Calcofluor White: decreased resistance to benzo[a]pyrene: decreased toxin resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	196 total interaction(s) for 126 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-RNA: 7 PCA: 3
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 48 Phenotypic Enhancement: 28 Phenotypic Suppression: 42 Positive Genetic: 8 Synthetic Growth Defect: 28 Synthetic Lethality: 24
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:370098 to 369697 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..402 370098..369697 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004100