AFB1/YLR040C Summary Help

Standard Name AFB1 1
Systematic Name YLR040C
Feature Type ORF, Verified
Description MATalpha-specific a-factor blocker; contributes to mating efficiency under certain conditions; localizes to the cell wall; predicted to be a GPI-attached protein; upregulated by Mcm1p-Alpha1p transcription factor; partially overlaps the dubious ORF YLR041W (1, 2, 3, 4, 5)
Name Description A-Factor Barrier 1
Chromosomal Location
ChrXII:229582 to 228908 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All AFB1 GO evidence and references
  View Computational GO annotations for AFB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1

Genetic Interactions
  • Negative Genetic: 6
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 224
Molecular Weight (Da) 24,462
Isoelectric Point (pI) 4.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:229582 to 228908 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..675 229582..228908 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004030
References cited on this page View Complete Literature Guide for AFB1
1) Huberman LB and Murray AW  (2013) Genetically engineered transvestites reveal novel mating genes in budding yeast. Genetics 195(4):1277-90
2) Hamada K, et al.  (1999) Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. J Bacteriol 181(13):3886-9
3) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
4) Galgoczy DJ, et al.  (2004) Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 101(52):18069-74
5) Brar GA, et al.  (2012) High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science 335(6068):552-7