ESL2/YKR096W Summary Help

ESL2 BASIC INFORMATION

Reserved Name ESL2 1

This name is reserved with SGD according to the Gene Naming Guidelines agreed upon by the yeast community.
For more information about this reservation, please see the Locus History.
Systematic Name YKR096W
Feature Type ORF, Verified
Description Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc domain (2, 3, 4, 5)
Name Description Est1A/B-Smg6/5-Like 1
GO Annotations All ESL2 GO evidence and references
    View Computational GO annotations for ESL2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All ESL2 Phenotype details and references
Large-scale survey
null
Interactions ESL2 All interactions details and references
18 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2
Genetic Interactions
  • Phenotypic Enhancement: 9
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 1
Sequence Information
ChrXI:626435 to 630022 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-12-15 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3588 626435..630022 2005-12-15 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001804

ESL2 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for ESL2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ESL2]

1) Lai X, et al.  (2008) DNA damage response functions of two Est1A/B-SMG6/5-Like (ESL) genes
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307
5) Bleichert F, et al.  (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9