Standard Name	EMC3 1
Systematic Name	YKL207W
Alias	AIM27 2
Feature Type	ORF, Verified
Description	Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response; homologous to worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111 (1, 2, 3)
Name Description	Altered Inheritance rate of Mitochondria 2

Chromosomal Location	ChrXI:48194 to 48955 | ORF Map | GBrowse

	View Computational GO annotations for EMC3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	protein folding in endoplasmic reticulum (IGI)
Cellular Component
Manually curated	ER membrane protein complex (IDA)
High-throughput	integral to membrane (ISM)

Retired Name	LRC3

Large-scale survey
null	respiratory growth: absent viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	49 total interaction(s) for 41 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-RNA: 3
Genetic Interactions	Negative Genetic: 19 Phenotypic Enhancement: 12 Positive Genetic: 3 Synthetic Growth Defect: 2 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:48194 to 48955 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2006-05-08
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..762 48194..48955 2011-02-03 2006-05-08
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001690