Standard Name	AAT1
Systematic Name	YKL106W
Feature Type	ORF, Verified
Description	Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis (1)
Name Description	Aspartate AminoTransferase 1

Chromosomal Location	ChrXI:237536 to 238891 | ORF Map | GBrowse

	View Computational GO annotations for AAT1
Molecular Function
Manually curated	L-aspartate:2-oxoglutarate aminotransferase activity (ISS)
Biological Process
Manually curated	asparagine biosynthetic process from oxaloacetate (IC) aspartate biosynthetic process (IMP) aspartate catabolic process (TAS) chronological cell aging (IMP) replicative cell aging (IMP)
Cellular Component
High-throughput	mitochondrion (IDA)

Pathways	asparagine biosynthesis asparagine degradation aspartate biosynthesis superpathway of threonine biosynthesis

Classical genetics
null	replicative lifespan: decreased
overexpression	chronological lifespan: increased replicative lifespan: increased silencing: increased
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to benzo[a]pyrene: decreased resistance to benzo[a]pyrene: increased respiratory growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	43 total interaction(s) for 37 unique genes/features.
Genetic Interactions	Negative Genetic: 19 Phenotypic Enhancement: 1 Phenotypic Suppression: 9 Positive Genetic: 12 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:237536 to 238891 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1356 237536..238891 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001589