DHR2/YKL078W Summary Help

Standard Name DHR2 1
Systematic Name YKL078W
Feature Type ORF, Verified
Description Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis (1)
Name Description DEAH-box RNA helicase 1
Chromosomal Location
ChrXI:288845 to 291052 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DHR2 GO evidence and references
  View Computational GO annotations for DHR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
dominant negative
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
41 total interaction(s) for 34 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • PCA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 14
  • Positive Genetic: 2
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 735
Molecular Weight (Da) 82,713
Isoelectric Point (pI) 9.43
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:288845 to 291052 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2208 288845..291052 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001561
References cited on this page View Complete Literature Guide for DHR2
1) Colley A, et al.  (2000) Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3. Mol Cell Biol 20(19):7238-46