DHR2/YKL078W Summary Help

Standard Name DHR2 1
Systematic Name YKL078W
Feature Type ORF, Verified
Description Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; required for 18S rRNA synthesis (1)
Name Description DEAH-box RNA helicase 1
Chromosomal Location
ChrXI:288845 to 291052 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DHR2 GO evidence and references
  View Computational GO annotations for DHR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 51 genes
Resources
Classical genetics
dominant negative
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
40 total interaction(s) for 33 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 14
  • Affinity Capture-Western: 2
  • PCA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 14
  • Positive Genetic: 2
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 735
Molecular Weight (Da) 82,713
Isoelectric Point (pI) 9.43
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:288845 to 291052 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2208 288845..291052 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001561
References cited on this page View Complete Literature Guide for DHR2
1) Colley A, et al.  (2000) Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3. Mol Cell Biol 20(19):7238-46