Standard Name	CCE1 (see Nomenclature conflict Note)
Systematic Name	YKL011C
Alias	MGT1
Feature Type	ORF, Verified
Description	Mitochondrial cruciform cutting endonuclease; cleaves Holliday junctions formed during recombination of mitochondrial DNA; CCE1 has a paralog, MRS1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	Cruciform Cutting Endonuclease 3

Chromosomal Location	ChrXI:421216 to 420155 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -2 cM

	View Computational GO annotations for CCE1
Molecular Function
Manually curated	endodeoxyribonuclease activity (IDA)
Biological Process
Manually curated	mitochondrial genome maintenance (IGI)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)

Classical genetics
null	resistance to erythromycin estolate: increased
Large-scale survey
null	dessication resistance: decreased resistance to benomyl: decreased resistance to hydroxyurea: decreased resistance to camptothecin: decreased resistance to 4-chlorophenol: decreased resistance to nickel(2+): decreased resistance to sorbate: increased resistance to cycloheximide: decreased resistance to streptomycin: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	10 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1
Genetic Interactions	Phenotypic Enhancement: 2 Synthetic Growth Defect: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:421216 to 420155 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -2 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1062 421216..420155 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001494