MET14/YKL001C Summary

MET14 BASIC INFORMATION

Standard Name	MET14 1
Systematic Name	YKL001C
Feature Type	ORF, Verified
Description	Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism (2)
Name Description	METhionine requiring 1

GO Annotations	All MET14 GO evidence and references
	View Computational GO annotations for MET14
Molecular Function
Manually curated	adenylylsulfate kinase activity (TAS)
Biological Process
Manually curated	methionine metabolic process (IMP) sulfate assimilation (NAS)
High-throughput	response to drug (IMP)
Cellular Component
Manually curated	cytoplasm (TAS) intracellular (IDA)

Pathways	sulfate assimilation pathway superpathway of sulfur amino acid biosynthesis

Mutant Phenotype	All MET14 Phenotype details and references
Classical genetics
null	auxotrophy
Large-scale survey
null	resistance to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO): decreased resistance to nickel(2+): decreased resistance to amiodarone: decreased resistance to nickel sulfate: decreased viable
overexpression	filamentous growth: increased

Interactions	MET14 All interactions details and references
	8 total interaction(s) for 6 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Two-hybrid: 4
Genetic Interactions	Phenotypic Enhancement: 2 Phenotypic Suppression: 1

Sequence Information

ChrXI:439028 to 438420 | |

Note: this feature is encoded on the Crick strand.

Genetic position: .8 cM

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..609	439028..438420	2005-12-15	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001484

MET14 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for MET14

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MET14]

1)	Masselot M and De Robichon-Szulmajster H (1975) Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants. Mol Gen Genet 139(2):121-32
2)	Donalies UE and Stahl U (2002) Increasing sulphite formation in Saccharomyces cerevisiae by overexpression of MET14 and SSU1. Yeast 19(6):475-84

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