YKE4/YIL023C Summary Help

Standard Name YKE4 1
Systematic Name YIL023C
Feature Type ORF, Verified
Description Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family (1)
Name Description Yeast ortholog of mouse KE4 1
Chromosomal Location
ChrIX:310426 to 309386 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YKE4 GO evidence and references
  View Computational GO annotations for YKE4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
30 total interaction(s) for 26 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • PCA: 2
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 15
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 346
Molecular Weight (Da) 37,418
Isoelectric Point (pI) 7.07
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:310426 to 309386 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1041 310426..309386 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001285
References cited on this page View Complete Literature Guide for YKE4
1) Kumanovics A, et al.  (2006) YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae. J Biol Chem 281(32):22566-74