NTA1/YJR062C Summary

NTA1 BASIC INFORMATION

Standard Name	NTA1
Systematic Name	YJR062C
Alias	DEA1
Feature Type	ORF, Verified
Description	Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation (1)
Name Description	N-Terminal Amidase 1

GO Annotations	All NTA1 GO evidence and references
	View Computational GO annotations for NTA1
Molecular Function
Manually curated	protein N-terminal asparagine amidohydrolase activity (IDA, IMP, ISS)
Biological Process
Manually curated	protein catabolic process (IMP) protein modification process (IMP)
Cellular Component
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All NTA1 Phenotype details and references
Classical genetics
null	prion formation: decreased resistance to rapamycin: increased
Large-scale survey
null	competitive fitness: decreased viable

Interactions	NTA1 All interactions details and references
	View additional details at BioGRID
	15 total interaction(s) for 14 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9
Genetic Interactions	Negative Genetic: 6

Sequence Information

ChrX:554841 to 553468 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2009-02-18 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1374	554841..553468	2009-02-18	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003823

NTA1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NTA1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NTA1]

1)	Baker RT and Varshavsky A (1995) Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway. J Biol Chem 270(20):12065-74

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