REC107/YJR021C Summary Help

Standard Name REC107 1
Systematic Name YJR021C
Alias MER2
Feature Type ORF, Verified
Description Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation (1, 2, 3, 4)
Name Description RECombination 1
Chromosomal Location
ChrX:469579 to 468555 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All REC107 GO evidence and references
  View Computational GO annotations for REC107
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
72 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Co-purification: 1
  • Protein-peptide: 1
  • Protein-RNA: 1
  • Two-hybrid: 47

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 5
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 314
Molecular Weight (Da) 35,683
Isoelectric Point (pI) 6.92
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:469579 to 468555 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..316 469579..469264 2011-02-03 1996-07-31
Intron 317..396 469263..469184 2011-02-03 1996-07-31
CDS 397..1025 469183..468555 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003782
References cited on this page View Complete Literature Guide for REC107
1) Malone RE, et al.  (1991) Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 128(1):79-88
2) Ohta K, et al.  (1998) Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc Natl Acad Sci U S A 95(2):646-51
3) Malone RE, et al.  (2004) The signal from the initiation of meiotic recombination to the first division of meiosis. Eukaryot Cell 3(3):598-609
4) Li J, et al.  (2006) Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation. Genetics 173(4):1969-81