GPI14/YJR013W Summary Help

Standard Name GPI14 1
Systematic Name YJR013W
Alias PMH1 2
Feature Type ORF, Verified
Description Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M (3, 4)
Name Description GlycosylPhosphatidylInositol anchor biosynthesis 1
Chromosomal Location
ChrX:460382 to 461593 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GPI14 GO evidence and references
  View Computational GO annotations for GPI14
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
Resources
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 3
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 403
Molecular Weight (Da) 47,166
Isoelectric Point (pI) 9.86
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:460382 to 461593 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2004-02-12
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1212 460382..461593 2011-02-03 2004-02-12
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003774
References cited on this page View Complete Literature Guide for GPI14
1) Kinoshita T and Inoue N  (2000) Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis. Curr Opin Chem Biol 4(6):632-8
2) Keranen, S  (2003) personal communication
3) Maeda Y, et al.  (2001) PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER. EMBO J 20(1-2):250-61
4) Ashida H, et al.  (2005) Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I. Mol Biol Cell 16(3):1439-48