Standard Name	RCY1 1
Systematic Name	YJL204C
Feature Type	ORF, Verified
Description	F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth (1, 2)
Name Description	ReCYcling 1

Chromosomal Location	ChrX:53151 to 50629 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RCY1
Molecular Function
Manually curated	SNARE binding (IMP, IPI)
Biological Process
Manually curated	early endosome to Golgi transport (IMP) endocytosis (IMP)
Cellular Component
Manually curated	endosome (IDA) Golgi apparatus (IDA) site of polarized growth (IDA)

Classical genetics
null	tellurium atom accumulation: decreased cold sensitivity: increased endocytosis: abnormal metal resistance: decreased carboxypeptidase Y (Prc1p) modification: decreased resistance to caffeine: decreased resistance to monensin: decreased resistance to tellurite: increased resistance to brefeldin A: decreased sporulation: absent vegetative growth: decreased rate
Large-scale survey
null	acid pH resistance: decreased alkaline pH resistance: decreased auxotrophy bud morphology: abnormal cell size: increased competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased metal resistance: decreased oxidative stress resistance: decreased resistance to caffeine: decreased resistance to BPS: decreased resistance to 2-phenyl-3-nitroso-imidazo[1,2-a]pyrimidine: decreased resistance to mefloquine: decreased resistance to chloroquine: decreased resistance to sodium selenide: decreased resistance to spermine: decreased resistance to hygromycin B: decreased resistance to 1,4-dithiothreitol: decreased resistance to tunicamycin: decreased resistance to methyl methanesulfonate: decreased resistance to amiodarone: decreased resistance to quinine: decreased resistance to (S)-lactic acid: decreased resistance to wortmannin: decreased resistance to arsenite(3-): decreased resistance to ethanol: decreased resistance to CTBT: decreased resistance to dihydromotuporamine C: decreased resistance to PM02734: decreased resistance to monensin: decreased resistance to mycophenolic acid: decreased resistance to miconazole: decreased resistance to rubidium chloride: decreased resistance to quercetin: decreased resistance to polymyxin B: decreased resistance to ruthenium red: decreased resistance to tetrindole mesylate: decreased resistance to trimethoprim: decreased resistance to zinc chloride: decreased resistance to GDP-beta-S: decreased resistance to nifedipine: decreased resistance to latrunculin B: decreased resistance to diltiazem-HCl: decreased resistance to diphenyleneiodonium: decreased resistance to cycloheximide: decreased resistance to cobalt dichloride: decreased resistance to cesium chloride: decreased resistance to beta-chloro-L-alanine: decreased resistance to chlorpromazine: decreased resistance to p-chloromercuribenzoic acid: decreased resistance to nordihydroguaiaretic acid: decreased resistance to Loperamide: decreased sporulation: decreased stress resistance: increased vacuolar morphology: abnormal vegetative growth: decreased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	53 total interaction(s) for 39 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-Western: 11 PCA: 2 Reconstituted Complex: 4 Two-hybrid: 5
Genetic Interactions	Dosage Growth Defect: 1 Dosage Lethality: 2 Positive Genetic: 1 Synthetic Growth Defect: 11 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 10 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:53151 to 50629 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2523 53151..50629 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003740