PRP21/YJL203W Summary Help

Standard Name PRP21 1
Systematic Name YJL203W
Alias SPP91
Feature Type ORF, Verified
Description Subunit of the SF3a splicing factor complex; required for spliceosome assembly (2)
Name Description Pre-mRNA Processing 1
Chromosomal Location
ChrX:53341 to 54183 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRP21 GO evidence and references
  View Computational GO annotations for PRP21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
Large-scale survey
null
reduction of function
repressible
Resources
156 total interaction(s) for 107 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 64
  • Co-purification: 1
  • Reconstituted Complex: 4
  • Two-hybrid: 22

Genetic Interactions
  • Negative Genetic: 57
  • Positive Genetic: 3
  • Synthetic Lethality: 3
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 280
Molecular Weight (Da) 33,052
Isoelectric Point (pI) 8.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:53341 to 54183 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..843 53341..54183 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003739
References cited on this page View Complete Literature Guide for PRP21
1) Vijayraghavan U, et al.  (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16
2) Hodges PE and Beggs JD  (1994) RNA splicing. U2 fulfils a commitment. Curr Biol 4(3):264-7