Standard Name	MNN11
Systematic Name	YJL183W
Feature Type	ORF, Verified
Description	Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p (1)
Name Description	MaNNosyltransferase

Chromosomal Location	ChrX:84068 to 85336 | ORF Map | GBrowse

	View Computational GO annotations for MNN11
Molecular Function
Manually curated	alpha-1,6-mannosyltransferase activity (IDA)
Biological Process
Manually curated	protein glycosylation (IDA, IMP)
Cellular Component
Manually curated	alpha-1,6-mannosyltransferase complex (IPI)

Classical genetics
null	sterol ester accumulation: increased protein secretion: increased Kss1p modification: increased resistance to Calcofluor White: decreased
Large-scale survey
null	acid pH resistance: decreased glutathione excretion: increased chitin deposition: increased competitive fitness: decreased endocytosis: decreased freeze-thaw resistance: decreased heat sensitivity: increased metal resistance: decreased protein transport: abnormal Can1p-GFP distribution: abnormal Fus-Mid-GFP distribution: abnormal resistance to Calcofluor White: decreased resistance to hydroxyurea: increased resistance to camptothecin: increased resistance to ethanol: decreased resistance to methanol: decreased resistance to sirolimus: decreased resistance to sulfometuron methyl: decreased resistance to acetic acid: decreased resistance to sodium arsenite: decreased resistance to propolis extract: decreased resistance to tunicamycin: decreased resistance to 1,4-dithiothreitol: decreased resistance to cycloheximide: decreased resistance to fenpropimorph: decreased resistance to fluconazole: decreased resistance to boric acid: decreased resistance to dimethyl sulfoxide: decreased resistance to mefloquine: decreased resistance to propan-1-ol: decreased resistance to doxorubicin: decreased resistance to sorbate: decreased toxin resistance: decreased vegetative growth: increased rate viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	469 total interaction(s) for 331 unique genes/features.
Physical Interactions	Affinity Capture-MS: 22 Affinity Capture-Western: 11 Co-purification: 1 PCA: 1 Two-hybrid: 6
Genetic Interactions	Negative Genetic: 325 Phenotypic Suppression: 2 Positive Genetic: 60 Synthetic Growth Defect: 19 Synthetic Lethality: 22
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:84068 to 85336 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1269 84068..85336 2011-02-03 2011-02-03
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003719