YAK1/YJL141C Summary Help

YAK1 BASIC INFORMATION

Standard Name YAK1 1
Systematic Name YJL141C
Feature Type ORF, Verified
Description Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal (2, 3, 4)
Name Description Yet Another Kinase 1
GO Annotations All YAK1 GO evidence and references
    View Computational GO annotations for YAK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Regulatory modules predicted: stressResponse ( 511 , 433 )
Mutant Phenotype All YAK1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions YAK1 All interactions details and references
61 total interaction(s) for 57 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 24
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 11
  • Two-hybrid: 2
Genetic Interactions
  • Dosage Rescue: 7
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1
Sequence Information
ChrX:150386 to 147963 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2424 150386..147963 2009-02-18 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003677

YAK1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for YAK1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YAK1]

1) Garrett S and Broach J  (1989) Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase. Genes Dev 3(9):1336-48
2) Garrett S, et al.  (1991) The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. Mol Cell Biol 11(8):4045-52
3) Kassis S, et al.  (2000) Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue. Biochem J 348 Pt 2():263-72
4) Moriya H, et al.  (2001) Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal. Genes Dev 15(10):1217-28