ALY2/YJL084C Summary Help

ALY2 BASIC INFORMATION

Standard Name ALY2 1, 2
Systematic Name YJL084C
Alias ART3 3
Feature Type ORF, Verified
Description Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin Pcl7p and ubiquitin ligase Rsp5p; phosphorylated by the cyclin-CDK complex, Pcl7p-Pho85p; mRNA is cell cycle regulated, peaking in M phase (4, 5, 6)
Name Description Arrestin-Like Yeast protein 1
GO Annotations All ALY2 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All ALY2 Phenotype details and references
Large-scale survey
null
Interactions ALY2 All interactions details and references
44 total interaction(s) for 37 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Biochemical Activity: 25
  • Reconstituted Complex: 1
  • Two-hybrid: 4

Sequence Information
ChrX:277996 to 274856 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2009-02-18 | Sequence: 1997-07-27
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3141 277996..274856 2009-02-18 1997-07-27
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003620

ALY2 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ALY2]

1) O' Donnell A  (2006) personal communication
2) Gupta R, et al.  (2007) Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Mol Syst Biol 3:116
3) Lin CH, et al.  (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25
4) Kumar A, et al.  (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19
5) Shi XZ and Ao SZ  (2002) Analysis of phosphorylation of YJL084c, a yeast protein. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 34(4):433-8
6) de Lichtenberg U, et al.  (2005) New weakly expressed cell cycle-regulated genes in yeast. Yeast 22(15):1191-201