LOH1/YJL038C Summary Help

Standard Name LOH1 1
Systematic Name YJL038C
Alias OSW4 2
Feature Type ORF, Verified
Description Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; proposed role in maintenance of genome integrity; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to adjacent ORF, IRC18/YJL037W, and the double mutant irc18 loh1 exhibits reduced dityrosine fluorescence relative to the single mutants (1, 2, 3, 4, 5)
Name Description Loss Of Heterozygosity 1
Chromosomal Location
ChrX:375774 to 375115 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All LOH1 GO evidence and references
  View Computational GO annotations for LOH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
3 total interaction(s) for 3 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 219
Molecular Weight (Da) 24,842
Isoelectric Point (pI) 7.2
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:375774 to 375115 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..660 375774..375115 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003575
References cited on this page View Complete Literature Guide for LOH1
1) Andersen MP, et al.  (2008) A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95
2) Suda Y, et al.  (2009) A screen for spore wall permeability mutants identifies a secreted protease required for proper spore wall assembly. PLoS One 4(9):e7184
3) Chu S, et al.  (1998) The transcriptional program of sporulation in budding yeast. Science 282(5389):699-705
4) McCord R, et al.  (2003) Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol Cell Biol 23(6):2009-16
5) Lin CP, et al.  (2013) A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae. PLoS Genet 9(8):e1003700