BBC1/YJL020C Summary Help

Standard Name BBC1 1
Systematic Name YJL020C
Alias MTI1 2 , YJL021C
Feature Type ORF, Verified
Description Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches (2, 3)
Name Description Bni1 synthetic lethal and Bee1 (las17) Complex member 4
Chromosomal Location
ChrX:402410 to 398937 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All BBC1 GO evidence and references
  View Computational GO annotations for BBC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
205 total interaction(s) for 127 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 22
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Biochemical Activity: 4
  • PCA: 7
  • Protein-peptide: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 59

Genetic Interactions
  • Negative Genetic: 46
  • Phenotypic Enhancement: 4
  • Positive Genetic: 4
  • Synthetic Growth Defect: 14
  • Synthetic Lethality: 36
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,157
Molecular Weight (Da) 128,296
Isoelectric Point (pI) 5.06
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:402410 to 398937 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): YJL021C | YJL020W-A
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2001-06-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3474 402410..398937 2011-02-03 2001-06-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003557
References cited on this page View Complete Literature Guide for BBC1
1) Tong AH, et al.  (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4
2) Mochida J, et al.  (2002) The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae. Genetics 160(3):923-34
3) Tong AH, et al.  (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8
4) Boone C  (2010) Personal Communication to SGD ()