YIP3/YNL044W Summary Help

Standard Name YIP3
Systematic Name YNL044W
Feature Type ORF, Verified
Description Protein localized to COPII vesicles; proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p (1, 2, 3)
Chromosomal Location
ChrXIV:545268 to 545877 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YIP3 GO evidence and references
  View Computational GO annotations for YIP3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
118 total interaction(s) for 76 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 10
  • Co-fractionation: 1
  • Co-purification: 3
  • PCA: 10
  • Two-hybrid: 27

Genetic Interactions
  • Negative Genetic: 45
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
  • Positive Genetic: 4
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 176
Molecular Weight (Da) 19,412
Isoelectric Point (pI) 8.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:545268 to 545877 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1999-11-17
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..24 545268..545291 2011-02-03 1999-11-17
Intron 25..103 545292..545370 2011-02-03 1999-11-17
CDS 104..610 545371..545877 2011-02-03 1999-11-17
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004989
References cited on this page View Complete Literature Guide for YIP3
1) Otte S, et al.  (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18
2) Calero M and Collins RN  (2002) Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins. Biochem Biophys Res Commun 290(2):676-81
3) Geng J, et al.  (2005) Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p. Eukaryot Cell 4(7):1166-74