YIP1/YGR172C Summary Help

Standard Name YIP1
Systematic Name YGR172C
Feature Type ORF, Verified
Description Integral membrane protein; required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF4 (1, 2, 3)
Chromosomal Location
ChrVII:843591 to 842845 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YIP1 GO evidence and references
  View Computational GO annotations for YIP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
conditional
null
overexpression
repressible
unspecified
Resources
88 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 7
  • Co-purification: 2
  • PCA: 3
  • Reconstituted Complex: 7
  • Two-hybrid: 31

Genetic Interactions
  • Dosage Rescue: 8
  • Negative Genetic: 2
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 23

Resources
Expression Summary
histogram
Resources
Length (a.a.) 248
Molecular Weight (Da) 27,080
Isoelectric Point (pI) 6.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:843591 to 842845 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..747 843591..842845 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003404
References cited on this page View Complete Literature Guide for YIP1
1) Heidtman M, et al.  (2003) A role for Yip1p in COPII vesicle biogenesis. J Cell Biol 163(1):57-69
2) Heidtman M, et al.  (2005) Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Mol Biol Cell 16(4):1673-83
3) Tanimoto K, et al.  (2011) Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip domain family proteins. Cell Struct Funct 36(2):171-85