| Standard Name | AIM20 1 |
|---|---|
| Systematic Name | YIL158W |
| Feature Type | ORF, Verified |
| Description | Putative protein of unknown function; overexpression causes cell cycle delay or arrest; green fluorescent protein (GFP)-fusion protein localizes to vacuole; null mutant displays elevated frequency of mitochondrial genome loss; relocalizes from nucleus to cytoplasm upon DNA replication stress; AIM20 has a paralog, SKG1, that arose from the whole genome duplication (1, 2, 3, 4, 5) |
| Name Description | Altered Inheritance rate of Mitochondria 1 |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All AIM20 GO evidence and references
| View Computational GO annotations for AIM20 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated |
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| Cellular Component | |
| High-throughput |
Mutant phenotypes All AIM20 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| overexpression | |
| Large-scale survey | |
| null |
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| overexpression | |
| Resources |
interactions All AIM20 Interaction evidence and references
| 6 total interaction(s) for 6 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All AIM20 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 1994-12-10 | Sequence: 1994-12-10 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000001420 |
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References cited on this page View Complete Literature Guide for AIM20
| 1) | Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 |
| 2) | Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 |
| 3) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 4) | Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 |
| 5) | Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 |






