POG1/YIL122W Summary

POG1 BASIC INFORMATION

Standard Name	POG1
Systematic Name	YIL122W
Feature Type	ORF, Verified
Description	Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated (1, 2, 3)
Name Description	Promoter Of Growth 1

GO Annotations	All POG1 GO evidence and references
	View Computational GO annotations for POG1
Molecular Function
Manually curated	specific RNA polymerase II transcription factor activity (ISS)
Biological Process
Manually curated	re-entry into mitotic cell cycle after pheromone arrest (IGI, IMP)
Cellular Component
Manually curated	nuclear chromatin (IDA) nucleus (IDA)
High-throughput	nucleus (IDA)

Regulatory Role
Regulatory modules	predicted: cellcycle ( 305 )

Mutant Phenotype	All POG1 Phenotype details and references
Classical genetics
overexpression	resistance to lithium chloride: increased
Large-scale survey
null	filamentous growth: increased hyperosmotic stress resistance: decreased invasive growth: absent
overexpression	filamentous growth: increased

Interactions	POG1 All interactions details and references
	21 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Biochemical Activity: 2 Protein-peptide: 1 Protein-RNA: 1 Two-hybrid: 8
Genetic Interactions	Dosage Rescue: 2 Phenotypic Enhancement: 2 Synthetic Rescue: 3

Sequence Information

ChrIX:130607 to 131662 | |

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1056	130607..131662	1994-12-10	1994-12-10

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001384

POG1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for POG1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for POG1]

1)	Leza MA and Elion EA (1999) POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2. Genetics 151(2):531-43
2)	Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33
3)	Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64

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