Standard Name	POG1 1
Systematic Name	YIL122W
Feature Type	ORF, Verified
Description	Nuclear chromatin-associated protein of unknown function; overexpression promotes recovery from pheromone induced arrest and suppresses the stress sensitivity caused by a mutation in the E3 ubiquitin ligase Rsp5p; binds upstream of BAR1 and cell cycle-related genes; potential Cdc28p substrate; SBF regulated (1, 2, 3, 4)
Name Description	Promoter Of Growth 1

Chromosomal Location	ChrIX:130610 to 131665 | ORF Map | GBrowse

	View Computational GO annotations for POG1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	re-entry into mitotic cell cycle after pheromone arrest (IGI, IMP)
Cellular Component
Manually curated	nuclear chromatin (IDA)
High-throughput	nucleus (IDA)

Regulatory modules	predicted: cellcycle (305)

Classical genetics
overexpression	resistance to lithium chloride: increased
Large-scale survey
null	competitive fitness: decreased filamentous growth: increased haploinsufficient hyperosmotic stress resistance: decreased invasive growth: absent resistance to sorbate: decreased vacuolar morphology: abnormal
overexpression	filamentous growth: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	45 total interaction(s) for 40 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 3 Biochemical Activity: 1 Protein-peptide: 1 Protein-RNA: 1 Two-hybrid: 8
Genetic Interactions	Dosage Growth Defect: 5 Dosage Rescue: 2 Negative Genetic: 16 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Synthetic Growth Defect: 1 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:130610 to 131665 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1056 130610..131665 2011-02-03 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001384