MOB1/YIL106W Summary Help

MOB1 BASIC INFORMATION

Standard Name MOB1 1
Systematic Name YIL106W
Feature Type ORF, Verified
Description Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex (1, 2, 3, 4, 5)
Name Description Mps One Binder 1
GO Annotations All MOB1 GO evidence and references
    View Computational GO annotations for MOB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All MOB1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions MOB1 All interactions details and references
44 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 5
  • Biochemical Activity: 4
  • Co-crystal Structure: 1
  • Co-localization: 5
  • Reconstituted Complex: 4
  • Two-hybrid: 8
Genetic Interactions
  • Dosage Lethality: 4
  • Dosage Rescue: 3
  • Synthetic Lethality: 5
  • Synthetic Rescue: 2
Sequence Information
ChrIX:166412 to 167441 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1999-11-17 | Sequence: 1999-11-17
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..20 166412..166431 1999-11-17 1999-11-17
Intron 21..105 166432..166516 1999-11-17 1999-11-17
CDS 106..1030 166517..167441 1999-11-17 1999-11-17
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001368

MOB1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for MOB1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MOB1]

1) Luca FC and Winey M  (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46
2) Komarnitsky SI, et al.  (1998) DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein. Mol Cell Biol 18(4):2100-7
3) Yoshida S and Toh-e A  (2001) Regulation of the localization of Dbf2 and mob1 during cell division of saccharomyces cerevisiae. Genes Genet Syst 76(2):141-7
4) Mah AS, et al.  (2001) Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex. Proc Natl Acad Sci U S A 98(13):7325-30
5) Luca FC, et al.  (2001) Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit. Mol Cell Biol 21(20):6972-83