VHR1/YIL056W Summary Help

Standard Name VHR1 1
Systematic Name YIL056W
Feature Type ORF, Verified
Description Transcriptional activator; required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations; VHR1 has a paralog, VHR2, that arose from the whole genome duplication (1, 2)
Name Description VHt1 Regulator 1
Chromosomal Location
ChrIX:249991 to 251913 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All VHR1 GO evidence and references
  View Computational GO annotations for VHR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 11 genes
Resources
Large-scale survey
null
overexpression
Resources
14 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 640
Molecular Weight (Da) 71,420
Isoelectric Point (pI) 9.67
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:249991 to 251913 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1923 249991..251913 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001318
References cited on this page View Complete Literature Guide for VHR1
1) Weider M, et al.  (2006) Vhr1p, a new transcription factor from budding yeast, regulates biotin-dependent expression of VHT1 and BIO5. J Biol Chem 281(19):13513-24
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61