Standard Name	GVP36 1
Systematic Name	YIL041W
Feature Type	ORF, Verified
Description	BAR domain-containing protein that localizes to both early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis (1, 2, 3)
Name Description	Golgi Vesicle Protein 1

Chromosomal Location	ChrIX:276525 to 277505 | ORF Map | GBrowse

	View Computational GO annotations for GVP36
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	endocytosis (IMP) establishment or maintenance of actin cytoskeleton polarity (IMP) vacuole organization (IMP)
Cellular Component
Manually curated	integral to Golgi membrane (IDA)
High-throughput	cytoplasm (IDA)

Classical genetics
null	actin cytoskeleton morphology: abnormal endocytosis: decreased heat sensitivity: increased ionic stress resistance: decreased resistance to Latrunculin B: increased resistance to ethanol: decreased vacuolar morphology: abnormal viable
overexpression	cell cycle progression in M phase: decreased
Large-scale survey
null	glycogen accumulation: decreased glutathione excretion: increased competitive fitness: decreased hyperosmotic stress resistance: decreased resistance to tunicamycin: decreased resistance to neothyonidioside: decreased resistance to sirolimus: decreased resistance to wortmannin: normal resistance to 1,4-dithiothreitol: decreased resistance to sorbate: increased resistance to BPS: decreased resistance to elesclomol-Cu: decreased resistance to cycloheximide: decreased stress resistance: increased toxin resistance: decreased vacuolar morphology: abnormal vegetative growth: abnormal viable
overexpression	cell cycle progression: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	91 total interaction(s) for 66 unique genes/features.
Physical Interactions	Affinity Capture-MS: 12 Affinity Capture-RNA: 2 Biochemical Activity: 1 Co-purification: 2
Genetic Interactions	Negative Genetic: 67 Phenotypic Suppression: 1 Positive Genetic: 1 Synthetic Growth Defect: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:276525 to 277505 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..981 276525..277505 2011-02-03 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001303