TED1/YIL039W Summary Help

Standard Name TED1 1
Systematic Name YIL039W
Feature Type ORF, Verified
Description Conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) (1, 2)
Name Description Trafficking of Emp24p/Erv25p-dependent cargo Disrupted 1
Chromosomal Location
ChrIX:278426 to 279847 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All TED1 GO evidence and references
  View Computational GO annotations for TED1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
138 total interaction(s) for 77 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 45
  • Phenotypic Enhancement: 28
  • Phenotypic Suppression: 36
  • Positive Genetic: 17
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 473
Molecular Weight (Da) 54,927
Isoelectric Point (pI) 5.58
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:278426 to 279847 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1422 278426..279847 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001301
References cited on this page View Complete Literature Guide for TED1
1) Haass FA, et al.  (2007) Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A 104(46):18079-18084
2) Dilda PJ, et al.  (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47