DOT5/YIL010W Summary Help

Standard Name DOT5 1
Systematic Name YIL010W
Feature Type ORF, Verified
Description Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth (2)
Name Description Disruptor Of Telomeric silencing 1
Chromosomal Location
ChrIX:334882 to 335529 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DOT5 GO evidence and references
  View Computational GO annotations for DOT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
33 total interaction(s) for 31 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 3
  • Reconstituted Complex: 3
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Growth Defect: 4
  • Negative Genetic: 15
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 215
Molecular Weight (Da) 24,119
Isoelectric Point (pI) 10.13
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:334882 to 335529 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..648 334882..335529 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001272
References cited on this page View Complete Literature Guide for DOT5
1) Singer MS, et al.  (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32
2) Cha MK, et al.  (2003) Nuclear thiol peroxidase as a functional alkyl-hydroperoxide reductase necessary for stationary phase growth of Saccharomyces cerevisiae. J Biol Chem 278(27):24636-43